The SPURS (Salinity Processes in the Upper Ocean Regional Study) project is NASA-funded oceanographic process study and associated field program that aim to elucidate key mechanisms responsible for near-surface salinity variations in the oceans. The project involves two field campaigns and a series of cruises in regions of the Atlantic and Pacific Oceans exhibiting salinity extremes. SPURS employs a suite of state-of-the-art in-situ sampling technologies that, combined with remotely sensed salinity fields from the Aquarius/SAC-D, SMAP and SMOS satellites, provide a detailed characterization of salinity structure over a continuum of spatio-temporal scales. The SPURS-2 campaign involved two month-long cruises by the R/V Revelle in August 2016 and October 2017 combined with complementary sampling on a more continuous basis over this period by the schooner Lady Amber. Focused around a central mooring located near 10N,125W, the objective of SPURS-2 was to study the dynamics of the rainfall-dominated surface ocean at the western edge of the eastern Pacific fresh pool subject to high seasonal variability and strong zonal flows associated with the North Equatorial Current and countercurrent. The SPURS central mooring consisted of a surface meteorological package, surface oceanographic instruments, and subsurface, non-real time oceanographic instruments including CTD, ADCP sensors and point current meters providing continuous series of temperature, salinity and current profile data. Meteorological observations included wind speed, air temperature, precipitation, and radiative flux. The mooring was deployed in 4769 m depth of water on 24 August 2016, at N10:03.0481, W125:01.939, and was recovered on November 11, 2017. WHOI mooring netCDF data files include surface and subsurface time series of sea temperature, skin temperature, salinity, conductivity, wind velocity, air temperature, relative humidity, precipitation rate, barometric pressure, shortwave and longwave radiation, short/longwave flux, heat Flux, wind Speed and direction.