small-RNA sequencing of sEV isolated from plasma of astronauts

We sought to determine whether the spaceflight environment can induce alterations in small extracellular vesicles (sEV) smallRNA content and their utility as biomarkers. Using small RNA sequencing (sRNAseq), we evaluated the impact of the spaceflight environment on sEV miRNA content in peripheral blood (PB) plasma of 14 astronauts, who flew STS missions between 1998-2001. Samples were collected at three-time points:10 days before the launch (L-10), the day of return (R-0), and three days post-landing (R+3).

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Field	Value
Maintainer	Open Science Data Repository Help Desk
Last Updated	August 10, 2026, 17:35 (UTC)
Created	April 1, 2025, 20:14 (UTC)
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harvest_source_title	Science Discovery Engine
identifier	10.26030/0n5d-ag77
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