HARV replication of the BRIC-23 Bacillus subtilis spaceflight

Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to replicate those transcriptome changes using High Aspect Ratio Vessels (HARVs). B. subtilis spores were grown in HARVs using the same protocol and growth conditions as the BRIC-23 spaceflight mission. RNA was extracted from the HARV samples and sequenced for differential expression analysis. HARV differentially expressed genes were then compared to the genes identified as differentially expressed in the BRIC-23 mission to access the accuracy of HARVs as a model for spaceflight experiments.

Data and Resources

Additional Info

Field Value
Maintainer GeneLab Outreach
Last Updated April 23, 2025, 22:59 (UTC)
Created April 1, 2025, 00:01 (UTC)
accessLevel public
accrualPeriodicity irregular
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harvest_object_id 661a597c-1a73-4e28-9d6e-c7f97f2fa125
harvest_source_id 61638e72-b36c-4866-9d28-551a3062f158
harvest_source_title DNG Legacy Data
identifier nasa_genelab_GLDS-216_saqd-3ded
issued 2021-05-21
landingPage https://data.nasa.gov/dataset/harv-replication-of-the-bric-23-bacillus-subtilis-spaceflight
license http://www.usa.gov/publicdomain/label/1.0/
modified 2023-01-26
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publisher National Aeronautics and Space Administration
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