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Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic...
RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver... -
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC)...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
Microbial Observatory (ISS-MO): Molecular characterization of Bacillus...
As part of an ongoing effort to catalogue microbial communities inhabiting the International Space Station (ISS) crew-associated environmental samples were collected from the... -
Transcriptomic analysis of spleens from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse spleens using a ground-based model for spaceflight. This model includes prolonged unloading and low-... -
Transcriptomic analysis of liver from mice subjected to simulated...
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression analysis.... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Eruca sativa Rocket Science RNA-seq
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop... -
Spatially resolved transcriptional analysis of hearts from mice flown on the...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU)...
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Streptococcus mutans differential gene expression in response to simulated...
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors... -
Kineosporiaceae bacterium B12 whole genome shotgun sequencing project
Rubinsicoccus jplei genome a novel genus isolated from JPL spacecraft environment where Mars 2020 subsystems are assembled. -
Impact of spaceflight on gene expression in the thymus
The thymus undergoes atrophy during spaceflight. In this study we analyzed gene expression of the thymus of mice on board International space station to elucidate molecular... -
RNA-Seq transcriptome analysis of reactive oxygen species gene network in...
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Transcriptome analysis of murine spleen in space
Our study aims to comprehensively understand effects induced by the space environment on mammals. To achieve this aim we analyze the male mice housed under environments as the... -
Adaptive changes in the vestibular system of land snail to a 30-day...
The vestibular system receives a permanent influence from gravity and reflexively controls equilibrium. If we assume gravity has remained constant during the species evolution... -
Analysis of dust samples from the Russian part of the ISS
Our study focuses on the hardiest microorganisms inhabiting the ISS in order to assess their diversity and capabilities to resist certain stresses. We specifically selected dust... -
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
BRIC-23 GeneLab Process Verification Test: Bacillus subtilis transcriptomic...
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned spaceflight...