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Transcriptomic analysis of spleens from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse spleens using a ground-based model for spaceflight. This model includes prolonged unloading and low-... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU)...
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Hindlimb suspension and reloading study
Analysis of effect of hindlimb suspension and reloading on C57Bl/6 mouse soleus muscle. Experimental groups examined: -Control mice 14 days -Hindlimb suspension for 7 days... -
Impact of Antiorthostatic Suspension on Mouse response to Tetanus Toxoid and...
These data were generated from mice that were skeletally unloaded using antiorthostatic suspension (AOS). Mice were either subjected to AOS or tail restraint without unloading... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Impact of Antiorthostatic Suspension on Mouse response to Tetanus Toxoid and CpG
These data were generated from mice that were skeletally unloaded using antiorthostatic suspension (AOS). Mice were either subjected to AOS or tail restraint without unloading... -
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of ability to... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Transcriptomic analysis of skin from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse skin using a ground-based model for spaceflight. This model includes prolonged unloading and low-dose... -
RNA-Seq transcriptome profiling of soleus from adult and aged mice following...
Rodent hind limb unloading was used as a model for reduced muscle activity and eventual atrophy. After a 10 day period of unloading mice in this study were xe2 x80 x9creloaded... -
Transcription profiling of rat to study the effect of hindlimb unloading on...
A recent physiological study established that hindlimb unloading of rats at 3 and 7 weeks inhibits healing of injured ligaments resulting in a badly aligned discontinuous... -
Effect of microgravity on brain gene expression in mice
Changes in gravitational force such as that experienced by astronauts during space flight induce a redistribution of fluids from the caudad to the cephalad portion of the body... -
Effect of microgravity on brain gene expression in mice
Changes in gravitational force such as that experienced by astronauts during space flight induce a redistribution of fluids from the caudad to the cephalad portion of the body... -
Expression profiling of soleus muscle under the effect of simulated spaceflight
Spaceflight imposes the risk of skeletal muscle atrophy for astronauts. The understanding of muscle atrophy because of spaceflight is limited but continued efforts are essential... -
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU)...
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-...