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Draft Genome Sequences of novel Agrobacterium genomospecies 3 Associated...
The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being part of Class... -
Diagnosing an Opportunistic Fungal Pathogen on Spaceflight-Grown Plants...
Sustainable agriculture in microgravity is integral to future long-term space exploration. To ensure the efficient and sustainable cultivation of plants in space, a contingency... -
Characterization of mouse ocular responses (intraocular pressure) to a...
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to... -
Effects of Spaceflight on Bone Microarchitecture in the Axial and...
This study investigated the effects of a 14-day spaceflight on bone mass, density and microarchitecture in weight bearing (femur and humerus) and non-weight bearing (2nd) lumbar... -
Transcriptional profiling of roots and shoots from Brachypodium distachyon...
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous model plant,... -
Quantifying Cancellous Bone Structural Changes in Microgravity: Axial...
Objective of this study was to further validate bone degradation in microgravity as site-specific and preferential to weight bearing bone. An objective of this study was to... -
Spaceflight-induced (STS-62) vertebral bone loss in ovariectomized rats is...
There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast differentiation. MAT... -
Altered rodent gait characteristics after ~35 days in orbit aboard the...
The long-term adaptations to microgravity and other spaceflight challenges within the confines of a spacecraft, and readaptations to weight-bearing upon reaching a destination,... -
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density in legs of... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Transcriptional profiling of thymus tissue from rats flown on the SLS-2 mission
The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science investigations. The... -
Advancing the automation of plant nucleic acid extraction for rapid...
Human space exploration missions will continue the development of sustainable plant cultivation in what are obviously novel habitat settings. Effective pathology mitigation... -
Characterization of Biofilm Formation, Growth, and Gene Expression on...
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance, biofilms... -
Toward countering muscle and bone loss with spaceflight: GSK3 as a potential...
We examined the effects of ~30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four... -
Arg1 functions in the physiological adaptation of undifferentiated plant...
In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1), a gene known to affect gravity... -
HSFA2 functions in the physiological adaptation of undifferentiated plant...
The Heat Shock Factor A2 (HsfA2), as a part of the HSF network, is essential to the plant's response to almost any environmental stress and to the cellular homeostatic control... -
Relevance of Unfolded Protein Response to Spaceflight-Induced...
Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human survival in... -
Microgravity effects on leaf morphology, cell structure, carbon metabolism...
The PESTO experiment was launched on April 8, 2002 onboard STS-110 (Atlantis) and was returned on June 19, 2002 onboard STS-111 (Endeavor), a total of 73 days in space. The...