-
Dynamic gene expression response to altered gravity in human T cells...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Microarray Analysis of Space-flown Murine Thymus Tissue
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene... -
Gene expression in human peripheral blood 48 hours after exposure to...
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to predict... -
Expression profiling of murine lung 70 days following exposure to...
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated controls or... -
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential... -
Action of microgravity on root development
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on vertical... -
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO)...
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special emphasis on... -
Dynamic nature of epigenetic patterns observed during the Mars 520-d mission...
Interplanetary human spaceflight represents a formidable medical challenge but also provides a unique platform for investigating human adaptation to extreme environmental... -
The development of Drosophila melanogaster during space flight
In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports the... -
Effect of electromagnetic fields on the chondrogenic differentiation under...
A combination therapy of electromagnetic fields (EMF) and simulated microgravity (SMG) has not been examined in regenerative medicine of cartilage. In the present study a... -
Gravitational signature of synchronized cell cultures in particular cell cycle stages
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome... -
Exposure of zebrafish larvae to relative microgravity between 5-6 days...
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason the... -
Molecular mechanism of flocculation self-recognition in yeast and its role...
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-expressing yeast... -
Gene expression response to simulated gravity and hypergravity in human T cells
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression... -
Immune responses to the in vitro LPS assault engineered in the spaceflight...
Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent environment for... -
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days...
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason the... -
Dynamic gene expression response to altered gravity in human T cells...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Exposure to ionizing radiation induced persistent gene expression changes in...
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was... -
Environmental and simulation facility conditions can modulate a...
Genome-wide transcriptional profiling shows that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene expression.... -
Comparative Transcriptomic Analysis of Adult Medaka Tissues Sampled after...
To understand how humans adapt to space environments many experiments can be conducted on astronauts while they work aboard the Space Shuttle or the International Space Station...