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Transcription profiling of atm mutant adm mutant and wild type whole plants...
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and... -
Chronic low dose-rate versus acute ionizing radiation induced gene...
Using a novel flood source construct we performed a direct comparison of genome-wide gene expression regulations resulting from exposure of primary human prostate fibroblast... -
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived...
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We... -
Plasticity of the human IgM repertoire in response to a long-term spaceflight
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are unknown.... -
Transcription profiling of Arabidopsis seedings exposed to UV-B irradiation
Interaction of COP1 and UVR8 which regulate UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis thaliana. -
Mouse femur LC-MSMS upon weightlessness
Bone loss and immune dysregulation are among the main adverse outcomes of spaceflight challenging astronaut xe2 x80 x99s health and safety. However consequences on B cell... -
Dynamic nature of epigenetic patterns observed during the Mars 520-d mission...
Interplanetary human spaceflight represents a formidable medical challenge but also provides a unique platform for investigating human adaptation to extreme environmental... -
Muscle atrophy osteoporosis prevention in hibernating mammals
Physical inactivity decreases the mechanical load on the skeleton which when prolonged leads to losses of muscle strength and bone mass in humans and most mammalian species.... -
Transcription profiling of Drosophila exposed to a levitation magnet for...
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5 mm of height... -
Temporal dynamics of the gut microbiota in people sharing a confined...
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated confinement such... -
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Non-targeted effects of low dose ionizing radiation act via TGF-beta to...
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after... -
Efficient Identification of Multiple Pathways: RNA-Seq Analysis of Livers...
Background: mRNA interactions with each other and other signaling molecules define different biological pathways and functions. Researchers have been investigating various tools... -
During development the Sku6 mutant roots engage different genes than wild...
The wild type Col-0 plants and the Sku-6 mutant plants of the Col-0 background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or 8... -
Galactic cosmic radiation induces stable epigenome alterations relevant to...
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in particular the... -
Non-targeted effects of low dose ionizing radiation act via TGF-beta to...
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after... -
The development of Drosophila melanogaster during space flight
In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports the... -
International Space Station - Microbial Observatory of Pathogenic Virus...
This study investigated the interplay between the microbial community of the International Space Station and its crew. Environmental samples were collected from 8 habitable... -
Transcription profiling of Drosophila exposed to a levitation magnet for...
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5 mm of height... -
Salivary microbiome sequencing of astronauts
This study s goal was to examine if any salivary microbiome changes were observed in astronauts as a result of spaceflight. In addition this study looked for any microbiome...