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Spaceflight effects on the mouse retina: Histological gene expression and...
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential... -
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant...
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight conditions. -
Microarray Analysis of Space-flown Murine Thymus Tissue
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene... -
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under...
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls. Cells were... -
A whole-genome microarray study of Arabidopsis thaliana cell cultures...
Arabidopsis thaliana wild type cell cultures were exposed to a 5-day space flight onboard of Shenzhou 8 to identify microgravity and space effect related gene expression. -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological... -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated... -
Dynamic gene expression response to altered gravity in human T cells...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Comparative gene expression analysis in the Arabidopsis thaliana root apex...
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Transcription profiling of mouse osteoblasts under static vs simulated microgravity
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to Affymetrix... -
Environmental and facility conditions promote singular gravity responses of...
Genome-wide transcriptional profiling showed that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene expression...