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Draft Genomes of Fungi Isolated from the International Space Station during...
Draft genomes of fungi isolated from different surfaces on the International Space Station, as part of the Microbial Tracking 2 mission (ISS-MOP). -
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7)...
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants’ adaption to environmental stressors.... -
Characterization of Epigenetic Regulation in an Extraterrestrial...
When germinated and grown on-board the ISS (International Space Station), plant do not exhibit abnormal structures but they do have altered growth habits and this project aims... -
Influence of gonadectomy on muscle health in micro- and partial-gravity...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
Combined space stressors induce independent behavioral deficits predicted by...
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to understand the... -
Influence of gonadectomy on muscle health in micro- and partial-gravity...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
Dose-dependent skeletal deficits due to varied reductions in mechanical...
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete... -
Simulated Galactic Cosmic Ray Exposure Activates Dose-Dependent DNA Repair...
This study's objective was to develop an understanding of the biological effects of space radiation on plants with the goal of producing fresh food during long duration space... -
Combined space stressors induce independent behavioral deficits predicted by...
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to understand the... -
Influence of gonadectomy on muscle health in micro- and partial-gravity...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
Influence of Sex Hormones on Nervous System and Musculoskeletal Health in...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
SpaceX Inspiration4 Dragon Capsule Metagenomic and Metatranscriptomic Microbial Swabs
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen samples... -
Persistence of Escherichia coli in the microbiomes of mizuna mustard...
Seed sanitization via chemical processes removes/reduces microbes from the external surfaces of the seed and thereby could have an impact on the plants' health or productivity.... -
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure -...
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron... -
Glycome profiling and immunohistochemistry uncover changes in cell walls of...
This study was conducted to uncover the underlying molecular mechanisms by which microgravity impacts cell wall architecture in the model plant Arabidopsis thaliana using the... -
STS-135 Liver Transcriptomics
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were shipped to... -
Expression data from C. elegans
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild type C.... -
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE)... -
Effects of low-dose oxygen ions and protons on cardiac function and...
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse effects of... -
Transcription profiling of rat response to changes in developmental stage -...
Transcriptional crosstalk between mammary gland, liver and adipose tissue Experiment Overall Design: Pregnant and Lactating rats exposed to 3 gravity conditions