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Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant...
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight conditions. -
Multi-omic investigations of mouse liver subjected to simulated spaceflight...
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage protocols... -
Microbial monitoring in the ISS-Kibo
Continuous monitoring of bacterial community structure in the ISS-Kibo. This data contains numerous sequence reads of 16S rRNA gene fragments. -
Dynamic gene expression response to altered gravity in human myelomonocytic...
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Comparative gene expression analysis in the Arabidopsis thaliana root apex...
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Expression Data from International C. elegans Experiment 1st (ICE-FIRST)
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray (Agilent). Overall design: Mix staged C. elegans N2 was exposed... -
Efficient Identification of Multiple Pathways: RNA-Seq Analysis of Livers...
Background: mRNA interactions with each other and other signaling molecules define different biological pathways and functions. Researchers have been investigating various tools... -
Whole genome sequencing and assembly of Eukaryotic microbes isolated from...
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline... -
Mouse fecal microbiome after exposure to high LET radiation
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose radiation... -
During development the Sku6 mutant roots engage different genes than wild...
The wild type Col-0 plants and the Sku-6 mutant plants of the Col-0 background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or 8... -
Spatially resolved transcriptional analysis of brains from mice flown on the...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Transcriptomic analysis of skin from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse skin using a ground-based model for spaceflight. This model includes prolonged unloading and low-dose... -
Whole genome sequencing and assembly of Eukaryotic microbes isolated from...
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline... -
Streptococcus mutans differential gene expression in response to simulated...
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors... -
Galactic cosmic radiation induces stable epigenome alterations relevant to...
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in particular the... -
RNA-Seq transcriptome analysis of reactive oxygen species gene network in...
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene... -
BRIC-23 GeneLab Process Verification Test: Staphylococcus aureus...
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned spaceflight... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse tibialis anterior...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
International Space Station flight project EXTREMOPHILES
The International Space Station (ISS) is a unique habitat for humans and microorganisms. Here, we report the results of the ISS experiment EXTREMOPHILES, including the analysis...