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Transcription profiling of mouse osteoblasts under static vs simulated microgravity
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to Affymetrix... -
Effect of a 91 day long stay in weightlessness on the International Space...
Comparative gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in the... -
Global gene expression profiles of cardiac progenitors differentiated from...
Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly modulate... -
Salivary microbiome sequencing of astronauts
This study s goal was to examine if any salivary microbiome changes were observed in astronauts as a result of spaceflight. In addition this study looked for any microbiome... -
Alteration of Proteomes in First-generation Cultures of Bacillus pumilus...
Bacillus pumilus SAFR-032 was originally isolated from the Jet Propulsion Lab Spacecraft Assembly Facility and thoroughly characterized for its enhanced resistance to UV... -
Environmental and facility conditions promote singular gravity responses of...
Genome-wide transcriptional profiling showed that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene expression... -
A study of gene expression influenced by simulated microgravity in human...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
Expression profiling of soleus muscle under the effect of simulated spaceflight
Spaceflight imposes the risk of skeletal muscle atrophy for astronauts. The understanding of muscle atrophy because of spaceflight is limited but continued efforts are essential... -
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU)...
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-... -
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli readily... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse gastrocnemius muscle...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources...