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miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Comparative gene expression analysis in the Arabidopsis thaliana root apex...
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Efficient Identification of Multiple Pathways: RNA-Seq Analysis of Livers...
Background: mRNA interactions with each other and other signaling molecules define different biological pathways and functions. Researchers have been investigating various tools... -
Whole genome sequencing and assembly of Eukaryotic microbes isolated from...
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline... -
Mouse fecal microbiome after exposure to high LET radiation
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose radiation... -
During development the Sku6 mutant roots engage different genes than wild...
The wild type Col-0 plants and the Sku-6 mutant plants of the Col-0 background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or 8... -
Spatially resolved transcriptional analysis of brains from mice flown on the...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Transcriptomic analysis of skin from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse skin using a ground-based model for spaceflight. This model includes prolonged unloading and low-dose... -
Whole genome sequencing and assembly of Eukaryotic microbes isolated from...
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline... -
Streptococcus mutans differential gene expression in response to simulated...
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors... -
Genetic Dissection of the Spaceflight Transcriptome Responses in Plants: are...
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and... -
RNA-Seq transcriptome analysis of reactive oxygen species gene network in...
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene... -
Dissecting transcriptional responses of nucleolin mutants to red light...
Understanding plant adaptive responses to the space environment is a requisite for enabling space farming. Spaceflight produce deleterious effects on plant cells particularly... -
BRIC-23 GeneLab Process Verification Test: Staphylococcus aureus...
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned spaceflight... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse tibialis anterior...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
International Space Station flight project EXTREMOPHILES
The International Space Station (ISS) is a unique habitat for humans and microorganisms. Here, we report the results of the ISS experiment EXTREMOPHILES, including the analysis... -
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse tibialis anterior...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
RNA-Seq transcriptome profiling of soleus from adult and aged mice following...
Rodent hind limb unloading was used as a model for reduced muscle activity and eventual atrophy. After a 10 day period of unloading mice in this study were xe2 x80 x9creloaded... -
Methylome Analysis of Arabidopsis Seedlings Exposed to Microgravity
DNA methylation is a very important kind of epigenetic modification and participates in many biological functions. Although many previous studies have addressed various plant...