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Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic...
RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver... -
Response of the EPI-200 human 3-D skin model to high and low doses of protons
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose responses. Most... -
Transcriptomic analysis of quadriceps from mice subjected to simulated...
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression analysis.... -
Mouse femur LC-MSMS upon weightlessness
Bone loss and immune dysregulation are among the main adverse outcomes of spaceflight challenging astronaut xe2 x80 x99s health and safety. However consequences on B cell... -
Synergistic effects of space radiation and microgravity (miRNA WT and dys-mutant)
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA... -
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Impact of Antiorthostatic Suspension on Mouse response to Tetanus Toxoid and CpG
These data were generated from mice that were skeletally unloaded using antiorthostatic suspension (AOS). Mice were either subjected to AOS or tail restraint without unloading... -
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast...
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle biological... -
Mouse muscle LC-MSMS upon weightlessness
Upon weightlessness and microgravity deleterious effects on the neurosensory and neurovestibular systems haematological changes and deconditioning of musculoskeletal... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse gastrocnemius muscle...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Dynamic gene expression response to altered gravity in human myelomonocytic...
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Temporal dynamics of the gut microbiota in people sharing a confined...
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated confinement such... -
Identification of miRNAs involved in cell response to ionising radiation and...
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation.... -
RNA-Seq transcriptome analysis of reactive oxygen species gene network in...
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene... -
Microbial monitoring in the ISS-Kibo
Continuous monitoring of bacterial community structure in the ISS-Kibo. This data contains numerous sequence reads of 16S rRNA gene fragments. -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological...