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Characterization of mouse ocular responses (Microscopy) to a 35-day (RR-9)...
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to... -
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are...
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight... -
Characterization of Biofilm Formation, Growth, and Gene Expression on...
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance, biofilms... -
Characterization of mouse ocular response to a 35-day spaceflight mission:...
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to... -
Transcriptional profiling of mammary glands from mice flown on the RRRM-1 mission
In Rodent Research Reference Mission-1 (RRRM-1), also known as RR-8, forty female BALB/cAnNTac mice were flown on the International Space Station. To assess differences in... -
Gene expression profiling for spaceflight induced-neuroinflammation in the...
The health risk from spaceflight-induced neuronal damage and potential adverse neurovascular effects is a chief concern. More recently, it has been proposed that... -
Predicting how varying moisture conditions impact the microbiome of dust...
On Earth, people spend 90% of their time indoors where dust and moisture can facilitate rapid microbial growth, especially fungi. The International Space Station is a... -
Single-molecule long-read methylation profiling reveals regional DNA...
The Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04-EpEx) experiment onboard the International Space Station examined the spaceflight-altered cytosine methylation... -
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7)...
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental stressors.... -
SpaceX Inspiration4 Stool Metagenome Profiling
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen samples... -
Spatial characterization of microbial communities on multi-species leafy...
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data. This... -
Spatial characterization of microbial communities on multi-species leafy...
Investigates the microbial communities of plants and Veggie pillow components with culturable and non-culturable methods providing qualitative and quantitative data. This... -
Characterization of Epigenetic Regulation in an Extraterrestrial...
When germinated and grown on-board the ISS (International Space Station), plant do not exhibit abnormal structures but they do have altered growth habits and this project aims... -
Draft Genomes of Fungi Isolated from the International Space Station during...
Draft genomes of fungi isolated from different surfaces on the International Space Station, as part of the Microbial Tracking 2 mission (ISS-MOP). -
Characterizing Epigenetic Changes in Methylation Mutants (elp2-5 and met1-7)...
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants’ adaption to environmental stressors.... -
Influence of gonadectomy on muscle health in micro- and partial-gravity...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
Combined space stressors induce independent behavioral deficits predicted by...
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to understand the... -
Dose-dependent skeletal deficits due to varied reductions in mechanical...
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete... -
Influence of gonadectomy on muscle health in micro- and partial-gravity...
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro-... -
Combined space stressors induce independent behavioral deficits predicted by...
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to understand the...